| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Sherman Darren | President and Chief Operating Officer, Director | C/O ORCHESTRA BIOMED HOLDINGS, INC., 150 UNION SQUARE DRIVE, NEW HOPE | /s/ Andrew Taylor, Attorney-in-Fact | 2025-08-25 | 0001723524 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | OBIO | Common Stock, par value $0.0001 per share | Purchase | $7.86K | +3K | +0.32% | $2.62 | 927K | Aug 25, 2025 | Direct |
President and Chief Operating Officer