| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Foresite Labs, LLC | 10%+ Owner | 601 CALIFORNIA STREET, SUITE 600, SAN FRANCISCO | FORESITE LABS, LLC, By: /s/ James B. Tananbaum, Manager | 2025-11-25 | 0002027905 |
| Foresite Labs Affiliates 2021, LLC | 10%+ Owner | 601 CALIFORNIA STREET, SUITE 600, SAN FRANCISCO | FORESITE LABS AFFILIATES 2021, LLC, By: Foresite Labs, LLC, Its: Managing Member, By: /s/ James B. Tananbaum, Manager | 2025-11-25 | 0002028005 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ALMS | Common Stock | Purchase | $533K | +72.2K | +2.84% | $7.38 | 2.61M | Nov 21, 2025 | See Footnote | F1 |
| holding | ALMS | Common Stock | 4.25M | Nov 21, 2025 | See Footnote | F2 | |||||
| holding | ALMS | Common Stock | 5.58M | Nov 21, 2025 | See Footnote | F3 | |||||
| holding | ALMS | Common Stock | 194K | Nov 21, 2025 | See Footnote | F4 | |||||
| holding | ALMS | Common Stock | 1.96M | Nov 21, 2025 | See Footnote | F5 | |||||
| holding | ALMS | Common Stock | 1.18M | Nov 21, 2025 | See Footnote | F6 |
| Id | Content |
|---|---|
| F1 | The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities. |
| F2 | The shares are held of record by Foresite Capital Fund VI, L.P. ("Fund VI"). Foresite Capital Management VI, LLC ("FCM VI") is the general partner of Fund VI and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCM VI, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Fund VI, disclaims beneficial ownership of the shares held by Fund VI, except to the extent of such person's pecuniary interest in such securities. |
| F3 | The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities. |
| F4 | The shares are held of record by Labs Co-Invest V, LLC ("Labs Co-Invest"). FCM V is the managing member of Labs Co-Invest and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Labs Co-Invest, disclaims beneficial ownership of the shares held by Labs Co-Invest, except to the extent of such person's pecuniary interest in such securities. |
| F5 | The shares are held of record by Foresite Labs Fund I, L.P. ("Labs Fund I"). Foresite Labs Management I, LLC ("FLM I") is the general partner of Labs Fund I and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FLM I, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Labs Fund I, disclaims beneficial ownership of the shares held by Labs Fund I, except to the extent of such person's pecuniary interest in such securities. |
| F6 | The shares are held of record by Foresite Labs Affiliates 2021, LLC ("Labs Affiliates"). Foresite Labs, LLC ("Labs") is the managing member of Labs Affiliates and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, a manager of Labs, may be deemed to share voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Lab Affiliates, disclaims beneficial ownership of the shares held by Labs Affiliates, except to the extent of such person's pecuniary interest in such securities. |
This Form 4 is one of three Form 4s filed on the date hereof in respect of these transactions. The Reporting Persons for the other Form 4s are Tananbaum, Fund V, Opportunity Fund V, Labs Co-Invest, Fund VI, Labs Fund I, FCM V, FCOM V, FCM VI and FLM I.