Martine A. Rothblatt - Oct 29, 2025 Form 4 Insider Report for UNITED THERAPEUTICS Corp (UTHR)

Signature
/s/ John S. Hess, Jr. under Power of Attorney
Stock symbol
UTHR
Transactions as of
Oct 29, 2025
Transactions value $
-$2,576,869
Form type
4
Date filed
10/31/2025, 05:12 PM
Previous filing
Oct 30, 2025
Next filing
Nov 4, 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
ROTHBLATT MARTINE A Chairperson & CEO, Director C/O UNITED THERAPEUTICS CORPORATION, 1000 SPRING STREET, SILVER SPRING /s/ John S. Hess, Jr. under Power of Attorney 2025-10-30 0001106578

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction UTHR Common Stock Options Exercise $481K +4K +3076.92% $120.26 4.13K Oct 29, 2025 Direct F1
transaction UTHR Common Stock Sale -$477K -1.1K -26.63% $433.31 3.03K Oct 29, 2025 Direct F1
transaction UTHR Common Stock Sale -$870K -2K -66.01% $435.24 1.03K Oct 29, 2025 Direct F1
transaction UTHR Common Stock Sale -$396K -900 -87.38% $439.99 130 Oct 29, 2025 Direct F1
transaction UTHR Common Stock Options Exercise $481K +4K +3076.92% $120.26 4.13K Oct 30, 2025 Direct F1
transaction UTHR Common Stock Sale -$671K -1.5K -36.32% $447.14 2.63K Oct 30, 2025 Direct F1
transaction UTHR Common Stock Sale -$243K -541 -20.57% $448.43 2.09K Oct 30, 2025 Direct F1
transaction UTHR Common Stock Sale -$657K -1.46K -69.84% $450.23 630 Oct 30, 2025 Direct F1, F2
transaction UTHR Common Stock Sale -$226K -500 -79.37% $451.29 130 Oct 30, 2025 Direct F1
holding UTHR Common Stock 166 Oct 29, 2025 by Spouse
holding UTHR Common Stock 325K Oct 29, 2025 by Trust F3
holding UTHR Common Stock 258K Oct 29, 2025 by Trust F4
holding UTHR Common Stock 45.6K Oct 29, 2025 by Trust F5
holding UTHR Common Stock 16K Oct 29, 2025 by Trust F6

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction UTHR Stock Option Options Exercise $0 -4K -2.74% $0.00 142K Oct 29, 2025 Common Stock 4K $120.26 Direct F1
transaction UTHR Stock Option Options Exercise $0 -4K -2.82% $0.00 138K Oct 30, 2025 Common Stock 4K $120.26 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 This exercise and sale of stock options was pursuant to a pre-arranged 10b5-1 trading plan entered into by the reporting person on May 2, 2025. This plan will continue until the earlier of: (a) exhaustion of a tranche of 294,000 stock options that expire March 15, 2026; or (b) December 31, 2025.
F2 This transaction was executed in multiple trades at prices ranging from $450.115 to $450.27. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F3 Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries.
F4 Shares held in family trusts as to which the Reporting Person's spouse is sole trustee and sole beneficiary or co-trustee and settlor with power to revoke.
F5 Shares held in family trusts as to which the Reporting Person's spouse shares investment power and the Reporting Person and/or immediate family members are beneficiaries.
F6 Shares held in family trusts as to which the Reporting Person is sole trustee and sole beneficiary or co-trustee and settlor with power to revoke.