| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Hamdy Ahmed MD | CMO | 128 SPRING STREET, BUILDING C - SUITE 500, LEXINGTON | /s/ Diantha Duvall, Attorney-in-fact | 2025-05-05 | 0001458506 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CRIS | Employee stock option (right to buy) | Award | $496K | +200K | $2.48 | 200K | May 1, 2025 | Common Stock | 200K | $2.48 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | This stock option vests over four years, with 25% of the original 200,000 shares underlying the award vesting on May 1, 2026 and an additional 6.25% of the original number of shares underlying the award vesting on each successive three-month period thereafter, subject to continued service. |