Esteban Santos - 06 May 2025 Form 4 Insider Report for AMGEN INC (AMGN)

Role: EVP, Operations
Signature: /s/ Esteban Santos
Issuer symbol: AMGN
Transactions as of: 06 May 2025
Net transactions value: +$5,817,164
Form type: 4
Filing time: 08 May 2025, 21:01:21 UTC
Previous filing: 06 May 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Santos Esteban	EVP, Operations	ONE AMGEN CENTER DRIVE, THOUSAND OAKS	/s/ Esteban Santos	07 May 2025	0001677950

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	AMGN	Common Stock	Award	$0	+3,327	+4.6%	$0.000000	76,367	06 May 2025	Direct	F1, F2
holding	AMGN	Common Stock						882	06 May 2025	401K Plan	F3

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AMGN	Nqso (Right to Buy)	Award	$5,817,164	+21,510		$270.44	21,510	06 May 2025	Common Stock	21,510	$270.44	Direct	F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The Restricted Stock Units (RSUs) were granted pursuant to the Amgen Inc. Second Amended and Restated 2009 Equity Incentive Plan (the Equity Incentive Plan) and vest in four equal annual installments of 25% each, commencing on 5/6/2026. Vested RSUs will be paid in shares of the Company's common stock on a one-to-one basis.
F2	These shares include 373 Dividend Equivalents (DEs) granted pursuant to the Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited to the reporting person's unvested RSUs and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional share amount.
F3	These shares are acquired under the Company's 401(k) Plan and represent interests in the Company's stock fund as of this filing.
F4	These non-qualified stock options were granted pursuant to the Equity Incentive Plan and vest and are exercisable in four equal annual installments of 25% each, commencing on 5/6/2026.