Rachel Y. Martens - Jun 1, 2025 Form 3 Insider Report for LEXICON PHARMACEUTICALS, INC. (LXRX)

Role: VP, Partnerships & Corp Strat
Signature: /s/ Rachel Y. Martens
Stock symbol: LXRX
Transactions as of: Jun 1, 2025
Transactions value $: $0
Form type: 3
Date filed: 6/6/2025, 05:40 PM
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Martens Rachel Yap	VP, Partnerships & Corp Strat	2445 TECHNOLOGY FOREST BLVD, 11TH FLOOR, THE WOODLANDS	/s/ Rachel Y. Martens	2025-06-06	0002071589

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	LXRX	Common Stock						0	Jun 1, 2025	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
holding	LXRX	Restricted Stock Units							Jun 1, 2025	Common Stock	201K		Direct	F1, F2
holding	LXRX	Stock Option (Right to Buy)							Jun 1, 2025	Common Stock	201K	$0.70	Direct	F3
holding	LXRX	Stock Option (Right to Buy)							Jun 1, 2025	Common Stock	151K	$1.69	Direct	F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.
F2	Each restricted stock unit represents a contingent right to receive one share of common stock.
F3	Option vests with respect to 25% of the shares subject to the option on the first anniversary of grant, and vests 1/48th per month for each month of service thereafter.
F4	Option vests with respect to 25% of the shares subject to the option on the first anniversary of grant (10/7/2025) and vests 148th per month for each month of service thereafter.