- 
        Signature
      
- 
        /s/ Sean Flynn, as Attorney-in-Fact for Robert Zerbe
      
      
- 
        Stock symbol
      
- 
        VCEL
      
      
- 
        Transactions as of
      
- 
        Nov 22, 2024
      
      
- 
        Transactions value $
      
- 
        -$117,375
      
      
- 
        Form type
      
- 
        4
      
      
- 
        Date filed
      
- 
        11/25/2024, 04:05 PM
      
 
     
   
 
  
    Transactions Table
  
  
    
      
        
          | Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes | 
      
      
          
            | transaction | VCEL | Common Stock | Options Exercise | $32.6K | +2.5K | +9.4% | $13.05 | 29.1K | Nov 22, 2024 | Direct |  | 
          
            | transaction | VCEL | Common Stock | Sale | -$150K | -2.5K | -8.59% | $60.00 | 26.6K | Nov 22, 2024 | Direct | F1 | 
      
    
   
  
    Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)
  
  
    
      
        
          | Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes | 
      
      
          
            | transaction | VCEL | Stock Option (Right to Buy) | Options Exercise | $0 | +2.5K | +33.33% | $0.00 | 10K | Nov 22, 2024 | Common Stock | 2.5K | $13.05 | Direct | F2 | 
      
    
   
  
    * An asterisk sign (*) next to the price indicates that the price is likely invalid.
  
  Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
  Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
  
    Explanation of Responses: