| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Epstein David M. | Director | C/O GYRE THERAPEUTICS, INC., 12770 HIGH BLUFF DRIVE, SUITE 150, SAN DIEGO | /s/ Ruoyu Chen, as attorney-in-fact for David M. Epstein | 06 Jun 2025 | 0001488668 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | GYRE | Stock Option (Right to Buy) | Award | $0 | +26K | $0.00 | 26K | 04 Jun 2025 | Common Stock | 26K | $8.58 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | This option represents a right to purchase a total of 26,000 shares of the Issuer's common stock, which will vest in 12 equal monthly installments through June 4, 2026, subject to the Reporting Person's continued service to the Issuer through each vesting date. |