Dan Weng - Aug 18, 2025 Form 4 Insider Report for GYRE THERAPEUTICS, INC. (GYRE)

Role: Director
Signature: /s/ Ruoyu Chen, as attorney-in-fact for Dan Weng
Stock symbol: GYRE
Transactions as of: Aug 18, 2025
Transactions value $: $0
Form type: 4
Date filed: 8/26/2025, 04:09 PM
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Weng Dan	Director	C/O GYRE THERAPEUTICS, INC., 12770 HIGH BLUFF DRIVE, SUITE 150, SAN DIEGO	/s/ Ruoyu Chen, as attorney-in-fact for Dan Weng	2025-08-26	0002083482

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	GYRE	Stock Option (Right to Buy)	Award	$0	+52K		$0.00	52K	Aug 18, 2025	Common Stock	52K	$7.85	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This option represents a right to purchase a total of 52,000 shares of the Issuer's common stock, which will vest in 36 equal monthly installments through August 18, 2028, subject to the Reporting Person's continued service to the Issuer through each vesting date.