L. Becker Hewes - Oct 15, 2021 Form 4 Insider Report for Blueprint Medicines Corp (BPMC)

Role: Chief Medical Officer
Signature: /s/ Ariel Hurley, Attorney-in-Fact
Stock symbol: BPMC
Transactions as of: Oct 15, 2021
Transactions value $: -$26,550
Form type: 4
Date filed: 10/19/2021, 04:04 PM
Previous filing: Sep 17, 2021
Next filing: Nov 17, 2021
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	BPMC	Common Stock	Options Exercise	$48.3K	+729	+2.78%	$66.24	26.9K	Oct 15, 2021	Direct	F1
transaction	BPMC	Common Stock	Sale	-$74.8K	-729	-2.71%	$102.66	26.2K	Oct 15, 2021	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	BPMC	Stock Option (Right to Buy)	Options Exercise	$0	-729	-2.78%	$0.00	25.5K	Oct 15, 2021	Common Stock	729	$66.24	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Effected pursuant to a trading plan adopted on August 13, 2021 pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.
F2	This option was granted on June 1, 2020. This option vested with respect to 25% of the shares underlying the option on June 1, 2021 and as to an additional 1/48th of the shares underlying the option each month thereafter.