| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Patel Naimish | Chief Medical Officer | C/O CRISPR THERAPEUTICS, 105 WEST FIRST STREET, BOSTON | /s/ Elizabeth Ryland Waldinger, attorney-in-fact | 2025-10-03 | 0002021679 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CRSP | Stock Option (Right to Buy) | Award | $0 | +16.5K | $0.00 | 16.5K | Oct 3, 2025 | Common Shares | 16.5K | $67.74 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | This option was granted on October 3, 2025 with respect to 16,500 Common Shares. 100% of the shares will vest in 48 equal monthly installments, with the first vesting date of November 3, 2025. |