| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Manke Isaac | Director | Q32 BIO INC., 830 WINTER STREET, WALTHAM | /s/ Eric Bell, Attorney-in-Fact | 2025-10-27 | 0001622769 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | QTTB | Stock Option (Right to Buy) | Award | $0 | +53.5K | $0.00 | 53.5K | Oct 23, 2025 | Common Stock | 53.5K | $2.80 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date. |