| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Bloomer Aaron | EVP, Chief Financial Officer | C/O EXACT SCIENCES CORP, 5505 ENDEAVOR LANE, MADISON | /s/ Aaron Bloomer by Mark Busch, attorney-in- fact | 30 Dec 2025 | 0002019003 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | EXAS | Common Stock | Options Exercise | $0 | +38,715 | +284% | $0.000000 | 52,338 | 23 Dec 2025 | Direct | F1 |
| transaction | EXAS | Common Stock | Tax liability | $1,746,315 | -17,151 | -33% | $101.82 | 35,187 | 23 Dec 2025 | Direct | F2 |
| transaction | EXAS | Common Stock | Options Exercise | $0 | +24,384 | +69% | $0.000000 | 59,571 | 23 Dec 2025 | Direct | F1 |
| transaction | EXAS | Common Stock | Tax liability | $1,099,961 | -10,803 | -18% | $101.82 | 48,768 | 23 Dec 2025 | Direct | F2, F3 |
| holding | EXAS | Common Stock | 212 | 23 Dec 2025 | Held in 401(k) Plan |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | EXAS | Restricted Stock Units | Options Exercise | $0 | -38,715 | -100% | $0.000000 | 0 | 23 Dec 2025 | Common Stock | 38,715 | Direct | F4, F5 | |
| transaction | EXAS | Restricted Stock Units | Options Exercise | $0 | -24,384 | -85% | $0.000000 | 4,395 | 23 Dec 2025 | Common Stock | 24,384 | Direct | F4, F6 |
| Id | Content |
|---|---|
| F1 | Represents shares of common stock received upon vesting of a restricted stock unit award. |
| F2 | Represents shares of Common Stock retained by Exact Sciences Corporation (the "Issuer") for tax withholding purposes in connection with the net-settlement on the issuance of shares of Common Stock in respect to the vesting of certain restricted stock units. |
| F3 | In addition to the shares of Common Stock reported on this Form 4, which total 48,980 shares, Mr. Bloomer also holds, in the aggregate, an additional 4,395 unvested restricted stock units, with each restricted stock unit representing a contingent right to receive one share of Common Stock |
| F4 | Each restricted stock unit represents a contingent right to receive one share of common stock. |
| F5 | This award was scheduled to vest in three equal installments on April 15, 2026, April 15, 2027, and April 15, 2028, subject to the Reporting Person's continued service through such vesting date but the vesting of the portion reflected herein was accelerated in connection with the Section 280G Mitigation. |
| F6 | This award was scheduled to vest in four equal installments on February 27, 2026, February 26, 2027, February 29, 2028, and February 28, 2029, subject to the Reporting Person's continued service through such vesting date but the vesting of the portion reflected herein was accelerated in connection with the Section 280G Mitigation. |