| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| SMITH IAN F | Chief Executive Officer, Director | C/O STOKE THERAPEUTICS, INC., 45 WIGGINS AVENUE, BEDFORD | /s/ Jonathan Allan, Attorney-in-Fact | 14 Oct 2025 | 0001197032 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | STOK | Stock Option (Right to Buy) | Award | $0 | +570K | $0.00 | 570K | 08 Oct 2025 | Common Stock | 570K | $30.50 | Direct | F1 | |
| transaction | STOK | Restricted Stock Units | Award | $0 | +380K | $0.00 | 380K | 08 Oct 2025 | Common Stock | 380K | Direct | F2, F3 |
| Id | Content |
|---|---|
| F1 | The option shall vest as to 1/4 of the total award on October 6, 2026, with an additional 1/48 of the total award vesting monthly thereafter, subject to the reporting person's continued service to the Issuer on each vesting date. |
| F2 | Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock upon settlement. |
| F3 | The award shall vest as to 1/4 of the total award annually on the sixth calendar day of October, subject to the reporting person's continued service to the Issuer on each vesting date, with the first tranche vesting on October 6, 2026. |