ANTONIO L. DELISE - 31 Jan 2022 Form 4 Insider Report for MARKETAXESS HOLDINGS INC (MKTX)

Role: Global Head of Corp. Dev.
Signature: /s/ Jason Edelstein, as Attorney-in-Fact for Antonio L. DeLise
Issuer symbol: MKTX
Transactions as of: 31 Jan 2022
Net transactions value: -$475,382
Form type: 4
Filing time: 02 Feb 2022, 15:15:15 UTC
Previous filing: 17 Aug 2021
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	MKTX	Common Stock, par value $0.003 per share	Award	$0	+1,274	+4.7%	$0.000000	28,373	31 Jan 2022	Direct	F1
transaction	MKTX	Common Stock, par value $0.003 per share	Tax liability	$117,468	-341	-1.2%	$344.48	28,032	31 Jan 2022	Direct	F2
transaction	MKTX	Common Stock, par value $0.003 per share	Tax liability	$106,100	-308	-1.1%	$344.48	27,724	31 Jan 2022	Direct	F2
transaction	MKTX	Common Stock, par value $0.003 per share	Tax liability	$74,752	-217	-0.78%	$344.48	27,507	31 Jan 2022	Direct	F3
transaction	MKTX	Common Stock, par value $0.003 per share	Tax liability	$48,572	-141	-0.51%	$344.48	27,366	31 Jan 2022	Direct	F4
transaction	MKTX	Common Stock, par value $0.003 per share	Tax liability	$18,602	-54	-0.2%	$344.48	27,312	31 Jan 2022	Direct	F4
transaction	MKTX	Common Stock, par value $0.003 per share	Tax liability	$43,404	-126	-0.46%	$344.48	27,186	31 Jan 2022	Direct	F3
transaction	MKTX	Common Stock, par value $0.003 per share	Tax liability	$66,485	-193	-0.71%	$344.48	26,993	31 Jan 2022	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

ANTONIO L. DELISE is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may continue.

Explanation of Responses:

Id	Content
F1	Represents a grant of restricted stock units pursuant to the Company's 2020 Equity Incentive Plan. The restricted stock units will vest in three installments of 34% on January 31, 2023, and 33% on each of January 31, 2024 and January 31, 2025.
F2	Represents the surrender of shares to the Company to satisfy Mr. DeLise's tax withholding obligation upon the receipt of vested restricted stock units that had been previously deferred by Mr. DeLise.
F3	Represents the surrender of shares to the Company to satisfy Mr. DeLise's tax withholding obligation upon the vesting of restricted stock units previously granted to Mr. DeLise.
F4	Represents the surrender of shares to the Company to satisfy Mr. DeLise's tax withholding obligation upon the vesting of shares of restricted stock previously granted to Mr. DeLise.