Nick Pizzie - 04 Mar 2022 Form 4 Insider Report for Axsome Therapeutics, Inc. (AXSM)

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AXSM	Employee Stock Option (Right to Buy)	Award	$0	+77,872		$0	77,872	04 Mar 2022	Common Stock	77,872	$29.91	Direct	F1
transaction	AXSM	Restricted Stock Units	Award	$0	+41,176		$0	41,176	04 Mar 2022	Common Stock	41,176		Direct	F2, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Id	Content
F1	The option will vest in substantially equal quarterly installments over four years such that the option will be fully vested on March 4, 2026.
F2	Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.
F3	25% of the RSUs will vest on the one (1) year anniversary of the date of grant. The remaining RSUs will vest in in three substantially equal annual installments, such that the RSUs will be fully vested on March 4, 2026. Vested shares will be delivered to the reporting person upon the earlier of (i) the closing of a Change in Control (as defined in the Issuer's Amended and Restated 2015 Omnibus Incentive Compensation Plan (the "Plan"), (ii) the reporting person's separation of service from the Issuer (including termination with or without Cause (as defined in the Plan), or termination due to death or disability), or (iii) seven (7) years from the date of grant.