| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Krishnan Krish S | President and CEO, Director, 10%+ Owner | C/O KRYSTAL BIOTECH, INC., 2100 WHARTON STREET, SUITE 701, PITTSBURGH | /s/ Krish S. Krishnan | 2025-07-16 | 0001298709 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | KRYS | Common Stock | Sale | -$2.01M | -13.4K | -0.88% | $150.30 | 1.51M | Jul 14, 2025 | Direct | F1, F2 |
| transaction | KRYS | Common Stock | Sale | -$329K | -2.18K | -0.14% | $150.68 | 1.51M | Jul 15, 2025 | Direct | F1, F3 |
| transaction | KRYS | Common Stock | Sale | -$137K | -900 | -0.06% | $151.79 | 1.51M | Jul 15, 2025 | Direct | F1, F4 |
| transaction | KRYS | Common Stock | Sale | -$208K | -1.39K | -0.09% | $150.00 | 1.51M | Jul 16, 2025 | Direct | F1, F4 |
| transaction | KRYS | Common Stock | Sale | -$2M | -13.3K | -0.92% | $150.29 | 1.44M | Jul 14, 2025 | By Spouse | F6, F7, F8 |
| transaction | KRYS | Common Stock | Sale | -$15.1K | -100 | -0.01% | $151.00 | 1.44M | Jul 14, 2025 | By Spouse | F4, F6, F8 |
| transaction | KRYS | Common Stock | Sale | -$337K | -2.24K | -0.15% | $150.68 | 1.44M | Jul 15, 2025 | By Spouse | F6, F8, F9 |
| transaction | KRYS | Common Stock | Sale | -$121K | -800 | -0.06% | $151.79 | 1.44M | Jul 15, 2025 | By Spouse | F4, F6, F8 |
| transaction | KRYS | Common Stock | Sale | -$229K | -1.53K | -0.11% | $150.00 | 1.44M | Jul 16, 2025 | By Spouse | F4, F6, F8 |
| holding | KRYS | Common Stock | 90K | Jul 14, 2025 | By Krishnan Spousal Trust | ||||||
| holding | KRYS | Common Stock | 50K | Jul 14, 2025 | By Krishnan Family Trust | F5 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan started on September 12, 2024, and contemplated quarterly sales of 25,000 shares of Common Stock. The Rule 10b5-1 trading plan has reached the maximum number of shares to be sold under such plan and has terminated. |
| F2 | The transaction was executed in multiple trades ranging from $150.00 to $150.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein. |
| F3 | The transaction was executed in multiple trades ranging from $150.21 to $151.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein. |
| F4 | The transaction was executed in one trade. |
| F5 | Directly beneficially owned by the Krishnan Family Trust. The Reporting Person and his spouse are each joint beneficial owners of the trust with joint voting and investment control. |
| F6 | The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person's spouse, Suma M. Krishnan. The Rule 10b5-1 trading plan started on September 12, 2024, and contemplated quarterly sales of 25,000 shares of Common Stock. The Rule 10b5-1 trading plan has reached the maximum number of shares to be sold under such plan and has terminated. |
| F7 | The transaction was executed in multiple trades ranging from $150.00 to $150.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein. |
| F8 | Directly beneficially owned by Suma M. Krishnan, the spouse of the Reporting Person. |
| F9 | The transaction was executed in multiple trades ranging from $150.21 to $151.18. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein. |