Tracey L. McCain - 01 Mar 2022 Form 4 Insider Report for Blueprint Medicines Corp (BPMC)

Role: EVP AND CHIEF LEGAL OFFICER
Signature: /s/ Ariel Hurley, Attorney-in-Fact
Issuer symbol: BPMC
Transactions as of: 01 Mar 2022
Transactions value $: $0
Form type: 4
Filing time: 03 Mar 2022, 19:02:37 UTC
Previous filing: 09 Dec 2021
Next filing: 08 Mar 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	BPMC	Common Stock	Award	$0	+12,500	+37.38%	$0	45,941	01 Mar 2022	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	BPMC	Stock Option (Right to Buy)	Award	$0	+25,000		$0	25,000	01 Mar 2022	Common Stock	25,000	$61.31	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The reported transaction involved the Reporting Person's receipt of grant of 12,500 restricted stock units under Issuer's 2015 Stock Option and Incentive Plan.
F2	This option vests with respect to 1/48th of the shares underlying the option on April 1, 2022 and as to an additional 1/48th of the shares underlying the option each month thereafter.