Crespo Blas Coll - Mar 15, 2025 Form 4 Insider Report for Structure Therapeutics Inc. (GPCR)

Role: Chief Medical Officer
Signature: /s/ Jun Yoon, Attorney-in-Fact
Stock symbol: GPCR
Transactions as of: Mar 15, 2025
Transactions value $: $0
Form type: 4
Date filed: 3/18/2025, 08:45 PM
Previous filing: Sep 20, 2024
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	GPCR	Ordinary Shares	Award	$0	+117K	+114.02%	$0.00	220K	Mar 15, 2025	Direct	F1, F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	GPCR	Employee Stock Option (right to buy)	Award	$0	+284K		$0.00	284K	Mar 15, 2025	Ordinary Shares	284K	$7.02	Direct	F1, F3, F4
transaction	GPCR	American Depositary Shares	Award	$0	+363	+99.45%	$0.00	728	Nov 20, 2024	Ordinary Shares	1.09K		Direct	F1, F5, F6
holding	GPCR	American Depositary Shares						1K	Mar 15, 2025	Ordinary Shares	3K		By spouse	F1, F5

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer.
F2	Represents the grant of restricted stock units ("RSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer. The RSUs vest 1/4th annually on each anniversary of March 1, 2025, subject to Reporting Person's continued service on such dates.
F3	The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs.
F4	1/4th of the shares subject to the option shall vest March 1, 2026, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date.
F5	Each ADS is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The ADSs have no expiration date.
F6	Voluntary reporting of the acquisition of 363 ADSs by the Reporting Person on Novembery 20, 2024 pursuant to the Issuer's Employee Share Purchase Plan.