| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Burow Kristina | Director | 301 BINNEY STREET, CAMBRIDGE | /s/ Junlin Ho, Attorney-in-Fact for Kristina Burow | 2025-05-30 | 0001569248 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | SRRK | Common Stock | Sale | -$29.2K | -1K | -3.78% | $29.24 | 25.5K | May 29, 2025 | Direct | F1, F2, F3 |
| transaction | SRRK | Common Stock | Sale | -$131K | -4.4K | -17.27% | $29.83 | 21.1K | May 29, 2025 | Direct | F1, F4, F5 |
| holding | SRRK | Common Stock | 2.35M | May 29, 2025 | See footnote | F6, F7 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | This sale was effected pursuant to a Rule 10b5-1 trading plan adopted on February 27, 2025 to cover tax withholding obligations upon the vesting and settlement of RSUs. |
| F2 | The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $28.57 to $29.49, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request. |
| F3 | Consists of 17,839 shares of common stock and 7,632 RSUs. |
| F4 | The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $29.59 to $30.18, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request. |
| F5 | Consists of 13,439 shares of common stock and 7,632 RSUs. |
| F6 | The shares are held by ARCH Venture Fund VIII, L.P. ("ARCH VIII"). ARCH Venture Partners VIII, L.P. ("GPLP"), as the sole general partner of ARCH VIII, may be deemed to beneficially own the shares held by ARCH VIII. ARCH Venture Partners VIII, LLC ("GPLLC"), as the sole general partner of GPLP, may be deemed to beneficially own the shares held by GPLP. The GPLP and GPLLC disclaim beneficial ownership of such securities, except to the extent of any pecuniary interest therein. |
| F7 | The managing directors of the GPLLC are Keith L. Crandell, Clinton Bybee and Robert Nelsen, and they may be deemed to beneficially own the shares held by ARCH VIII. Messrs. Crandell, Bybee and Nelsen disclaim beneficial ownership of such shares, except to the extent of any pecuniary interest therein. The Reporting Person is a managing director of the GPLP. The Reporting Person owns an interest in the GPLP but does not have voting or investment control over the shares held by ARCH VIII. The Reporting Person disclaims ownership of such shares, except to the extent of her pecuniary interest therein. |