Patrick Machado - 30 Jul 2025 Form 4 Insider Report for ALUMIS INC. (ALMS)

Role: Director
Signature: /s/ Sanam Pangali, Attorney-in-Fact
Issuer symbol: ALMS
Transactions as of: 30 Jul 2025
Net transactions value: $0
Form type: 4
Filing time: 01 Aug 2025, 16:05:08 UTC
Previous filing: 20 Jun 2025
Next filing: 10 Dec 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Machado Patrick	Director	C/O ALUMIS INC., 280 EAST GRAND AVENUE, SOUTH SAN FRANCISCO	/s/ Sanam Pangali, Attorney-in-Fact	01 Aug 2025	0001311210

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ALMS	Stock Option (Right to Buy)	Award	$0	+49,800		$0.000000	49,800	30 Jul 2025	Common Stock	49,800	$4.10	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The shares underlying this option vest on the first anniversary of the date of grant, provided that the shares will in any case be fully vested on the date of the Issuer's 2026 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2024 Equity Incentive Plan (the "Plan")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan), subject to the Reporting Person's Continuous Service (as defined in the Plan) through such date.

Content

The shares underlying this option vest on the first anniversary of the date of grant, provided that the shares will in any case be fully vested on the date of the Issuer's 2026 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2024 Equity Incentive Plan (the "Plan")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan), subject to the Reporting Person's Continuous Service (as defined in the Plan) through such date.