Gilad Mamlok - Aug 24, 2025 Form 3 Insider Report for Protalix BioTherapeutics, Inc. (PLX)

Role: Sr. VP and CFO
Signature: /s/ Gilad Mamlok
Stock symbol: PLX
Transactions as of: Aug 24, 2025
Transactions value $: $0
Form type: 3
Date filed: 8/25/2025, 04:31 PM
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Mamlok Gilad	Sr. VP and CFO	CO PROTALIX BIOTHERAPEUTICS, INC., CARMIEL, ISRAEL	/s/ Gilad Mamlok	2025-08-25	0001975896

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
holding	PLX	Stock Option (Right to Buy)							Aug 24, 2025	Common Stock	598K	$1.45	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The shares of common stock underlying the stock options shall vest in 12 equal quarterly installments commencing upon the date of grant. The stock options are subject to accelerated vesting upon a corporate transaction or a change in control as described in the Protalix BioTherapeutics, Inc., Amended and Restated 2006 Stock Incentive Plan, as amended.