Mark Mortenson - Sep 18, 2025 Form 4 Insider Report for Clene Inc. (CLNN)

Role: Chief Science Officer
Signature: /s/ Jerome T. Miraglia POA
Stock symbol: CLNN
Transactions as of: Sep 18, 2025
Transactions value $: $0
Form type: 4
Date filed: 9/19/2025, 03:48 PM
Previous filing: Feb 25, 2025
Next filing: Sep 30, 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Mortenson Mark	Chief Science Officer	6550 SOUTH MILLROCK DRIVE, SUITE G50, SALT LAKE CITY	/s/ Jerome T. Miraglia POA	2025-09-19	0001835427

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	CLNN	stock option	Award	$0	+10K		$0.00	10K	Sep 18, 2025	common stock	10K	$6.32	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This option was granted on September 18, 2025 as an option for 10,000 share of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $6.32 per share. The options vest immediately upon grant.