Robert Dee Etherington - 25 Sep 2025 Form 4/A - Amendment Insider Report for Clene Inc. (CLNN)

Role: President & CEO, Director
Signature: /s/ Jerome T. Miraglia POA
Issuer symbol: CLNN
Transactions as of: 25 Sep 2025
Transactions value $: $0
Form type: 4/A - Amendment
Filing time: 30 Sep 2025, 15:56:26 UTC
Date Of Original Report: 29 Sep 2025
Previous filing: 19 Sep 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Etherington Robert Dee	President & CEO, Director	6550 SOUTH MILLROCK DRIVE, SUITE G50, SALT LAKE CITY	/s/ Jerome T. Miraglia POA	30 Sep 2025	0001835330

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	CLNN	stock option	Award	$0	+40,000		$0	40,000	25 Sep 2025	common stock	40,000	$5.88	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This Form 4 amendment is being filed to correct a Form 4 filed on September 29, 2025. The corrected exercise price is $5.88 per share.
F2	This option was granted on September 25, 2025 as an option for 40,000 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $5.88 per share. The options vest in 12 equal monthly installments on the 25th day of each calendar month, beginning October 25, 2025, until such shares are fully vested.