MICHAEL PATRICK MILLER - 11 Nov 2025 Form 4 Insider Report for PUMA BIOTECHNOLOGY, INC. (PBYI)

Role: Director
Signature: /s/ Gordon Esplin as attorney-in-fact for Michael Patrick Miller
Issuer symbol: PBYI
Transactions as of: 11 Nov 2025
Transactions value $: -$97,228
Form type: 4
Filing time: 13 Nov 2025, 16:41:21 UTC
Previous filing: 13 Jun 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
MILLER MICHAEL PATRICK	Director	C/O PUMA BIOTECHNOLOGY, INC., 10880 WILSHIRE BLVD., SUITE 2150, LOS ANGELES	/s/ Gordon Esplin as attorney-in-fact for Michael Patrick Miller	13 Nov 2025	0001236514

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	PBYI	Common Stock	Sale	-$97.2K	-20K	-27.03%	$4.86	54K	11 Nov 2025	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.82 to $4.97, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

Content

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.82 to $4.97, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.