James Burns - Mar 1, 2025 Form 4 Insider Report for AGIOS PHARMACEUTICALS, INC. (AGIO)

Role
Chief Legal Officer
Signature
/s/ William Cook, as Attorney in Fact for James Burns
Stock symbol
AGIO
Transactions as of
Mar 1, 2025
Transactions value $
-$142,338
Form type
4
Date filed
3/4/2025, 04:17 PM
Previous filing
Nov 12, 2024
Next filing
Jun 26, 2025
SEC
View on sec.gov

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction AGIO Common stock Options Exercise $0 +3.83K +24.03% $0.00 19.8K Mar 1, 2025 Direct F1
transaction AGIO Common stock Sale -$40.4K -1.14K -5.75% $35.54 18.7K Mar 3, 2025 Direct F2
transaction AGIO Common stock Options Exercise $0 +4K +21.45% $0.00 22.7K Mar 1, 2025 Direct
transaction AGIO Common stock Sale -$42.2K -1.19K -5.24% $35.54 21.5K Mar 3, 2025 Direct F3
transaction AGIO Common stock Options Exercise $0 +5.67K +26.4% $0.00 27.1K Mar 1, 2025 Direct
transaction AGIO Common stock Sale -$59.7K -1.68K -6.2% $35.54 25.4K Mar 3, 2025 Direct F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction AGIO Restricted stock units Award $0 +12K $0.00 12K Mar 1, 2025 Common stock 12K Direct F5, F6
transaction AGIO Restricted stock units Award $0 +11.8K $0.00 11.8K Mar 1, 2025 Common stock 11.8K Direct F5, F6
transaction AGIO Stock options (right to buy) Award $0 +43.5K $0.00 43.5K Mar 1, 2025 Common stock 43.5K $35.54 Direct F7
transaction AGIO Restricted stock units Options Exercise $0 -3.83K -100% $0.00 0 Mar 1, 2025 Common stock 3.83K Direct F5, F8
transaction AGIO Restricted stock units Options Exercise $0 -4K -50% $0.00 4K Mar 1, 2025 Common stock 4K Direct F5, F9
transaction AGIO Restricted stock units Options Exercise $0 -5.67K -33.34% $0.00 11.3K Mar 1, 2025 Common stock 5.67K Direct F5, F10
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 Includes 254 shares purchased through the Company's employee stock purchase plan.
F2 Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's performance share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated March 1, 2022.
F3 Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's performance share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated March 1, 2023.
F4 Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's performance share units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated March 1, 2024.
F5 Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.
F6 The restricted stock units were granted on March 1, 2025. Beginning on March 1, 2026, the shares underlying the restricted stock units will vest in three equal annual installments.
F7 This option was granted on March 1, 2025. The shares underlying this option vest as to 25% of the underlying shares on March 1, 2026, with the remaining 75% vesting in 36 equal monthly installments thereafter.
F8 The restricted stock units were granted on March 1, 2022. Beginning on March 1, 2023, the shares underlying the restricted stock units will vest in three equal annual installments.
F9 The restricted stock units were granted on March 1, 2023. Beginning on March 1, 2024, the shares underlying the restricted stock units will vest in three equal annual installments.
F10 The restricted stock units were granted on March 1, 2024. Beginning on March 1, 2025, the shares underlying the restricted stock units will vest in three equal annual installments.