Mardi Dier - 12 Jun 2025 Form 4 Insider Report for Prelude Therapeutics Inc (PRLD)

Role: Director
Signature: /s/ Krishna Vaddi, Attorney-in-Fact
Issuer symbol: PRLD
Transactions as of: 12 Jun 2025
Net transactions value: $0
Form type: 4
Filing time: 13 Jun 2025, 16:15:27 UTC
Previous filing: 12 Mar 2025
Next filing: 03 Dec 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Dier Mardi	Director	C/O PRELUDE THERAPEUTICS INCORPORATED, 175 INNOVATION BOULEVARD, WILMINGTON	/s/ Krishna Vaddi, Attorney-in-Fact	13 Jun 2025	0001574591

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	PRLD	Director Stock Option (Right to Buy)	Award	$0	+38,000		$0.000000	38,000	12 Jun 2025	Common Stock	38,000	$1.04	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The option award will fully vest upon the earlier of (a) the Issuer's next annual stockholder meeting, or (b) the one-year anniversary of the grant date, such to the Reporting Person's provision of service to the Issuer on each vesting date.