AmirAli Talasaz - Mar 31, 2025 Form 4 Insider Report for Guardant Health, Inc. (GH)

Role: Co-Chief Executive Officer, Director
Signature: /s/ John G. Saia, as attorney-in-fact for AmirAli Talasaz
Stock symbol: GH
Transactions as of: Mar 31, 2025
Transactions value $: -$620,507
Form type: 4
Date filed: 4/2/2025, 05:26 PM
Previous filing: Mar 18, 2025
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	GH	Common Stock	Options Exercise	$0	+4.81K	+0.21%	$0.00	2.3M	Mar 31, 2025	Direct
transaction	GH	Common Stock	Tax liability	-$104K	-2.44K	-0.11%	$42.60	2.3M	Mar 31, 2025	Direct	F1
transaction	GH	Common Stock	Options Exercise	$0	+24K	+1.04%	$0.00	2.32M	Apr 1, 2025	Direct
transaction	GH	Common Stock	Tax liability	-$517K	-12.2K	-0.52%	$42.47	2.31M	Apr 1, 2025	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	GH	Restricted Stock Units	Options Exercise	$0	-4.81K	-25%	$0.00	14.4K	Mar 31, 2025	Common Stock	4.81K	$0.00	Direct	F2, F3
transaction	GH	Restricted Stock Units	Options Exercise	$0	-24K	-12.5%	$0.00	168K	Apr 1, 2025	Common Stock	24K	$0.00	Direct	F3, F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.
F2	This represents a restricted stock unit award granted on March 12, 2025 that vests in four equal installments on the last day of each calendar quarter, March 31, 2025, June 30, 2025, September 30, 2025, and December 31, 2025.
F3	Not applicable for Restricted Stock Units.
F4	This represents a restricted stock unit award granted on March 18, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vest in equal quarterly installments over the remaining two-year period thereafter.