- 
        Signature
      
 
      - 
        /s/ John B. Moriarty, Jr., J.D., Attorney-in-Fact
      
 
    
    
      
- 
        Stock symbol
      
 
      - 
        RNA
      
 
    
    
      
- 
        Transactions as of
      
 
      - 
        Oct 16, 2024
      
 
    
    
      
- 
        Transactions value $
      
 
      - 
        -$857,510
      
 
    
    
      
- 
        Form type
      
 
      - 
        4
      
 
    
    
      
- 
        Date filed
      
 
      - 
        10/17/2024, 04:20 PM
      
 
    
    
    
    
   
     
   
 
  
    Transactions Table
  
  
    
      
        
          | Type | 
          Sym | 
          Class | 
          Transaction | 
          Value $ | 
          Shares | 
          Change % | 
          * Price $ | 
          Shares After | 
          Date | 
          Ownership | 
          Footnotes | 
        
      
      
          
            | transaction | 
            RNA | 
            Common Stock | 
            Options Exercise | 
            $356K | 
            +25K | 
            +26.59% | 
            $14.22 | 
            119K | 
            Oct 16, 2024 | 
            Direct | 
            F1 | 
          
          
            | transaction | 
            RNA | 
            Common Stock | 
            Sale | 
            -$1.21M | 
            -25K | 
            -21.01% | 
            $48.52 | 
            94K | 
            Oct 16, 2024 | 
            Direct | 
            F1, F2 | 
          
      
    
   
  
    Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)
  
  
    
      
        
          | Type | 
          Sym | 
          Class | 
          Transaction | 
          Value $ | 
          Shares | 
          Change % | 
          * Price $ | 
          Shares After | 
          Date | 
          Underlying Class | 
          Amount | 
          Exercise Price | 
          Ownership | 
          Footnotes | 
        
      
      
          
            | transaction | 
            RNA | 
            Stock Option (Right to Buy) | 
            Options Exercise | 
            $0 | 
            -25K | 
            -18.87% | 
            $0.00 | 
            108K | 
            Oct 16, 2024 | 
            Common Stock | 
            25K | 
            $14.22 | 
            Direct | 
            F1, F3 | 
          
      
    
   
  
    * An asterisk sign (*) next to the price indicates that the price is likely invalid.
  
  Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
  Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
  
    Explanation of Responses: