Teresa McCarthy - Aug 15, 2025 Form 4 Insider Report for Avidity Biosciences, Inc. (RNA)

Signature
/s/ John B. Moriarty, Jr., J.D., Attorney-in-Fact
Stock symbol
RNA
Transactions as of
Aug 15, 2025
Transactions value $
-$242,232
Form type
4
Date filed
8/15/2025, 05:50 PM
Previous filing
Mar 21, 2025
Next filing
Sep 17, 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
McCarthy Teresa Chief Human Resources Officer C/O AVIDITY BIOSCIENCES, INC., 10578 SCIENCE CENTER DRIVE, SUITE 125, SAN DIEGO /s/ John B. Moriarty, Jr., J.D., Attorney-in-Fact 2025-08-15 0001862121

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction RNA Common Stock Options Exercise $223K +10K +10.3% $22.34 107K Aug 15, 2025 Direct F1
transaction RNA Common Stock Sale -$466K -10K -9.33% $46.56 97.1K Aug 15, 2025 Direct F1, F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction RNA Stock Option (Right to Buy) Options Exercise $0 -10K -9.09% $0.00 100K Aug 15, 2025 Common Stock 10K $22.34 Direct F1, F3
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on April 11, 2025.
F2 This represents a weighted-average price. These shares were sold in multiple transactions at prices ranging from $45.36 to $47.50. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F3 The shares subject to this option award are fully vested and exercisable as of the date hereof.