Sarah Boyce - Aug 28, 2025 Form 4 Insider Report for Avidity Biosciences, Inc. (RNA)

Signature
/s/ John B. Moriarty, Jr., J.D., Attorney-in-Fact
Stock symbol
RNA
Transactions as of
Aug 28, 2025
Transactions value $
-$1,203,700
Form type
4
Date filed
8/29/2025, 04:28 PM
Previous filing
Jun 26, 2025
Next filing
Sep 5, 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Boyce Sarah President and CEO, Director C/O AVIDITY BIOSCIENCES, INC., 10578 SCIENCE CENTER DRIVE, SUITE 125, SAN DIEGO /s/ John B. Moriarty, Jr., J.D., Attorney-in-Fact 2025-08-29 0001629383

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction RNA Common Stock Options Exercise $31K +25K +8.17% $1.24 331K Aug 28, 2025 Direct F1
transaction RNA Common Stock Sale -$1.23M -25K -7.56% $49.39 306K Aug 28, 2025 Direct F1, F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction RNA Stock Option (Right to Buy) Options Exercise $0 -25K -2.28% $0.00 1.07M Aug 28, 2025 Common Stock 25K $1.24 Direct F1, F3
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted on August 15, 2024 by the Reporting Person.
F2 This represents a weighted-average price. These shares were sold in multiple transactions at prices ranging from $49.23 to $49.52. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F3 This option award is fully vested and exercisable as of the date hereof.