| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Brady James Parker | Chief Human Resources Officer | C/O ARDELYX, INC., 400 FIFTH AVENUE, SUITE 210, WALTHAM | /s/ Elizabeth Grammer, Attorney-in-Fact for James Parker Brady | 2025-10-17 | 0002088887 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| holding | ARDX | Common Stock | 166K | Jun 18, 2025 | Direct | F1 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| holding | ARDX | Stock Option (Right to Buy) | Jun 18, 2025 | Common Stock | 250K | $3.93 | Direct | F2 |
| Id | Content |
|---|---|
| F1 | Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) shares of Common Stock for each one (1) RSU upon the vesting thereof. |
| F2 | Twenty Five Percent (25%) of the shares subject to the option vest on June 3, 2026 and the remaining shares subject to the option vest in 36 successive, equal monthly installments thereafter, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date. |
Exhibit 24.1 - Power of Attorney