Anish Bhatnagar - 15 Dec 2025 Form 4 Insider Report for SOLENO THERAPEUTICS INC (SLNO)

Role: CHIEF EXECUTIVE OFFICER, Director
Signature: /s/ Anish Bhatnagar
Issuer symbol: SLNO
Transactions as of: 15 Dec 2025
Net transactions value: -$380,619
Form type: 4
Filing time: 17 Dec 2025, 16:34:22 UTC
Previous filing: 31 Mar 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Anish Bhatnagar	CHIEF EXECUTIVE OFFICER, Director	100 MARINE PARKWAY, SUITE 400, REDWOOD CITY	/s/ Anish Bhatnagar	17 Dec 2025	0001614821

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	SLNO	Common Stock	Tax liability	$380,619	-7,620	-1.3%	$49.95	569,456	15 Dec 2025	Direct	F1, F2
transaction	SLNO	Common Stock	Gift	$0	-100,000	-18%	$0.000000	469,456	15 Dec 2025	Direct	F2, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents shares that have been withheld by the Issuer to satisfy the Reporting Person's tax withholding obligations in connection with the settlement of restricted stock units ("RSUs") which vested on December 15, 2025.
F2	Certain of these securities are RSUs. Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.
F3	On December 15, 2025, the Reporting Person transferred an aggregate of 100,000 shares of Common Stock as a gift to two family trusts for the benefit of his descendants, for no consideration. The Reporting Person is not a trustee and does not retain investment or voting control over the shares. Following the gift, the Reporting Person disclaims beneficial ownership of the shares held by the trusts and reports beneficial ownership herein only to the extent of any pecuniary interest, if any.