| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Dougan Brady W | Director | 2525 EAST NORTH CAROLINA HIGHWAY 54, DURHAM | /s/ Brady W. Dougan by Dale A. Sander as Attorney-in-Fact | 2025-11-17 | 0001878020 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | HUMA | Stock Options (right to buy) | Award | $0 | +311K | $0.00 | 311K | Nov 16, 2025 | Common Stock | 311K | $1.23 | By spouse | F1 |
| Id | Content |
|---|---|
| F1 | The first 1/3 of the option becomes exercisable on February 14, 2026, after which 1/3 of the option will become exercisable on November 16, 2026, and the remaining 1/3 of the option will become exercisable on November 16, 2027. |