| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| EDGEMOND JAMES | CFO AND TREASURER | C/O UNITED THERAPEUTICS CORPORATION, 1000 SPRING STREET, SILVER SPRING | /s/ John S. Hess, Jr. under Power of Attorney | 12 Nov 2025 | 0001636178 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | UTHR | Common Stock | Options Exercise | $3.07M | +21K | +258.68% | $146.03 | 29.1K | 10 Nov 2025 | Direct | F1 |
| transaction | UTHR | Common Stock | Sale | -$470K | -1.05K | -3.61% | $446.51 | 28.1K | 10 Nov 2025 | Direct | F1, F2 |
| transaction | UTHR | Common Stock | Sale | -$689K | -1.54K | -5.48% | $447.47 | 26.5K | 10 Nov 2025 | Direct | F1, F3 |
| transaction | UTHR | Common Stock | Sale | -$1.5M | -3.36K | -12.65% | $448.33 | 23.2K | 10 Nov 2025 | Direct | F1 |
| transaction | UTHR | Common Stock | Sale | -$293K | -653 | -2.82% | $449.00 | 22.5K | 10 Nov 2025 | Direct | F1, F4 |
| transaction | UTHR | Common Stock | Sale | -$270K | -600 | -2.66% | $450.80 | 21.9K | 10 Nov 2025 | Direct | F1, F5 |
| transaction | UTHR | Common Stock | Sale | -$481K | -1.07K | -4.86% | $451.87 | 20.9K | 10 Nov 2025 | Direct | F1, F6 |
| transaction | UTHR | Common Stock | Sale | -$982K | -2.17K | -10.41% | $452.76 | 18.7K | 10 Nov 2025 | Direct | F1, F7 |
| transaction | UTHR | Common Stock | Sale | -$2.1M | -4.63K | -24.8% | $453.81 | 14.1K | 10 Nov 2025 | Direct | F1, F8 |
| transaction | UTHR | Common Stock | Sale | -$1.52M | -3.34K | -23.79% | $454.82 | 10.7K | 10 Nov 2025 | Direct | F1, F9 |
| transaction | UTHR | Common Stock | Sale | -$1.18M | -2.59K | -24.19% | $455.83 | 8.12K | 10 Nov 2025 | Direct | F1, F10 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | UTHR | Stock Option | Options Exercise | $0 | -21K | -67.07% | $0.00 | 10.3K | 10 Nov 2025 | Common Stock | 21K | $146.03 | Direct |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | This exercise of stock options and subsequent sale of shares was pursuant to a Rule 10b5-1 trading plan entered into by the reporting person on August 5, 2025. |
| F10 | This transaction was executed in multiple trades at prices ranging from $455.35 to $456.27. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F2 | This transaction was executed in multiple trades at prices ranging from $445.81 to $446.80. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F3 | This transaction was executed in multiple trades at prices ranging from $446.81 to $447.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F4 | This transaction was executed in multiple trades at prices ranging from $448.82 to $449.59. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F5 | This transaction was executed in multiple trades at prices ranging from $450.24 to $451.05. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F6 | This transaction was executed in multiple trades at prices ranging from $451.31 to $452.30. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F7 | This transaction was executed in multiple trades at prices ranging from $452.32 to $453.20. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F8 | This transaction was executed in multiple trades at prices ranging from $453.34 to $454.33. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F9 | This transaction was executed in multiple trades at prices ranging from $454.35 to $455.34. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |