Dean J. Mitchell - Sep 24, 2025 Form 4 Insider Report for Praxis Precision Medicines, Inc. (PRAX)

Role
Director
Signature
/s/ Alex Nemiroff, as Attorney-in-Fact
Stock symbol
PRAX
Transactions as of
Sep 24, 2025
Transactions value $
$483,991
Form type
4
Date filed
9/25/2025, 04:40 PM
Previous filing
Jun 27, 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
MITCHELL DEAN J Director C/O PRAXIS PRECISION MEDICINES, INC., 99 HIGH STREET, 30TH FLOOR, BOSTON /s/ Alex Nemiroff, as Attorney-in-Fact 2025-09-25 0001199297

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction PRAX Common Stock Options Exercise $27.7K +1.93K +38.64% $14.36 6.93K Sep 24, 2025 Direct
transaction PRAX Common Stock Options Exercise $379K +8.57K +123.57% $44.25 15.5K Sep 24, 2025 Direct
transaction PRAX Common Stock Options Exercise $77.2K +1.75K +11.31% $44.04 17.3K Sep 24, 2025 Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction PRAX Stock Option (Right to Buy) Options Exercise $0 -1.93K -100% $0.00 0 Sep 24, 2025 Common Stock 1.93K $14.36 Direct F1
transaction PRAX Stock Option (Right to Buy) Options Exercise $0 -8.57K -100% $0.00 0 Sep 24, 2025 Common Stock 8.57K $44.25 Direct F2
transaction PRAX Stock Option (Right to Buy) Options Exercise $0 -1.75K -16.66% $0.00 8.77K Sep 24, 2025 Common Stock 1.75K $44.04 Direct F3
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 This option was fully vested as of June 12, 2024.
F2 This option was fully vested as of June 5, 2025.
F3 The shares subject to this option vest in twelve (12) equal monthly installments over one (1) year commencing on June 26, 2025.