Katherine Stueland - Sep 16, 2025 Form 4 Insider Report for GeneDx Holdings Corp. (WGS)

Role: CHIEF EXECUTIVE OFFICER, Director
Signature: /s/ Bridget Brown, Attorney-in-Fact
Stock symbol: WGS
Transactions as of: Sep 16, 2025
Transactions value $: -$1,275,585
Form type: 4
Date filed: 9/18/2025, 06:04 PM
Previous filing: Sep 11, 2025
Next filing: Oct 1, 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Stueland Katherine	CHIEF EXECUTIVE OFFICER, Director	C/O GENEDX HOLDINGS CORP., 333 LUDLOW ST., NORTH TOWER, 6TH FLOOR, STAMFORD	/s/ Bridget Brown, Attorney-in-Fact	2025-09-18	0001689575

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	WGS	Class A Common Stock	Options Exercise	$0	+18.8K	+296.26%	$0.00	25.1K	Sep 16, 2025	Direct	F1
transaction	WGS	Class A Common Stock	Sale	-$1.28M	-10.5K	-41.87%	$121.47	14.6K	Sep 16, 2025	Direct	F2, F3, F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	WGS	Restricted Stock Unit	Options Exercise	$0	-18.8K	-14.29%	$0.00	113K	Sep 16, 2025	Class A Common Stock	18.8K		Direct	F1, F5

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit ("RSU") represents a contingent right to receive 1 share of the Issuer's Class A Common Stock upon settlement for no consideration.
F2	The sale reported on this Form 4 represents shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The sale was to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary transaction by the Reporting Person.
F3	The price reported is a weighted average price. These shares were sold as part of a block trade for multiple security holders of the Issuer in multiple transactions at prices ranging from $118.28 to $123.07, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote 3 with regard to the block trade.
F4	Following the reported sales, in addition to the 14,578 shares of Class A common stock beneficially owned by the Reporting Person, the Reporting Person beneficially owned restricted stock units ("RSUs") representing contingent rights to receive up to an aggregate of 444,539 shares of Class A common stock and options to purchase up to an aggregate of 107,610 shares of Class A common stock, which RSUs and options vest according to their respective terms.
F5	6.25% vest in quarterly installments over the 4-year period commencing on March 16, 2023 until fully vested, subject to the Reporting Person's continued service to the Issuer on each vesting date.