Katherine Stueland - Oct 29, 2025 Form 4 Insider Report for GeneDx Holdings Corp. (WGS)

Role: CHIEF EXECUTIVE OFFICER, Director
Signature: /s/ Bridget Brown, Attorney-in-Fact
Stock symbol: WGS
Transactions as of: Oct 29, 2025
Transactions value $: -$294,654
Form type: 4
Date filed: 10/31/2025, 04:42 PM
Previous filing: Oct 1, 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Stueland Katherine	CHIEF EXECUTIVE OFFICER, Director	C/O GENEDX HOLDINGS CORP., 333 LUDLOW ST., NORTH TOWER, 6TH FLOOR, STAMFORD	/s/ Bridget Brown, Attorney-in-Fact	2025-10-31	0001689575

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	WGS	Class A Common Stock	Options Exercise	$0	+3.87K	+225.23%	$0.00	5.59K	Oct 29, 2025	Direct	F1
transaction	WGS	Class A Common Stock	Sale	-$294K	-2.15K	-38.51%	$136.54	3.44K	Oct 29, 2025	Direct	F2
transaction	WGS	Class A Common Stock	Sale	-$547	-4	-0.12%	$136.75	3.44K	Oct 29, 2025	Direct	F2, F3

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	WGS	Restricted Stock Unit	Options Exercise	$0	-3.87K	-33.33%	$0.00	7.75K	Oct 29, 2025	Class A Common Stock	3.87K		Direct	F1, F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit ("RSU") represents a contingent right to receive 1 share of the Issuer's Class A Common Stock upon settlement for no consideration.
F2	The sale reported on this Form 4 represents shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of RSUs. The sale was to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary transaction by the Reporting Person.
F3	Following the reported sale undertaken to satisfy tax withholding liabilities, in addition to the 3,436 shares of Class A Common Stock beneficially owned by the Reporting Person, the Reporting Person beneficially owned RSUs representing contingent rights to receive up to an aggregate of 440,665 shares of Class A Common Stock and options to purchase up to an aggregate of 107,610 shares of Class A Common Stock, which RSUs and options vest according to their respective terms.
F4	25% of the total award vested on each of April 29, 2023 and April 29, 2024, and an additional 6.25% of the total award vested or vests thereafter on each quarterly anniversary, subject to the Reporting Person's continued service to the Issuer on each vesting date, with the last tranche scheduled to vest on April 29, 2026. These RSUs do not have an expiration date; they either vest or are cancelled prior to the vesting date.