| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Stuart Iain | CHIEF SCIENTIFIC OFFICER | C/O VYNE THERAPEUTICS INC., 685 ROUTE 202/206 N, SUITE 301, BRIDGEWATER | /s/ Mutya Harsch, Attorney-in-Fact | 2025-10-02 | 0001727756 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VYNE | Common Stock | Tax liability | -$822 | -2.45K | -2.04% | $0.34 | 118K | Sep 30, 2025 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Represents shares that have been withheld by the Issuer to satisfy tax withholding requirements in connection with the vesting of restricted stock units. |