Christopher Missling - Oct 2, 2025 Form 4 Insider Report for ANAVEX LIFE SCIENCES CORP. (AVXL)

Role: President and CEO, Director
Signature: /s/Christopher Missling
Stock symbol: AVXL
Transactions as of: Oct 2, 2025
Transactions value $: $0
Form type: 4
Date filed: 10/3/2025, 08:41 PM
Previous filing: Sep 12, 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
MISSLING CHRISTOPHER U	President and CEO, Director	630 5TH AVENUE, 20TH FLOOR, NEW YORK	/s/Christopher Missling	2025-10-03	0001196573

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AVXL	Stock Option (Right to Buy)	Award	$0	+125K	+100%	$0.00	250K	Oct 2, 2025	Common Stock	125K	$5.36	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	On February 20, 2024, the reporting person was granted an option to purchase 500,000 shares of common stock. The option vests in four equal tranches based on four performance milestones, one of which was Readout of AV3-71-SZ-001 schizophrenia study. The performance criteria for this milestone was met, resulting in vesting of the option as to 125,000 shares.