Akshay Vaishnaw - 09 Aug 2021 Form 4 Insider Report for ALNYLAM PHARMACEUTICALS, INC. (ALNY)

Role: President, R&D
Signature: By: /s/ Mary Beth DeLena, Attorney-in-Fact For: Akshay K. Vaishnaw
Issuer symbol: ALNY
Transactions as of: 09 Aug 2021
Transactions value $: -$1,484,258
Form type: 4
Filing time: 11 Aug 2021, 16:10:02 UTC
Previous filing: 22 Jun 2021
Next filing: 23 Dec 2021
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ALNY	Common Stock	Options Exercise	$683K	+10.8K	+96.6%	$63.00	22K	09 Aug 2021	Direct	F1
transaction	ALNY	Common Stock	Sale	-$2.17M	-10.8K	-49.14%	$200.00	11.2K	09 Aug 2021	Direct	F1
holding	ALNY	Common Stock						515	09 Aug 2021	by Managed Account	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ALNY	Performance Stock Option 2013 (right to buy)	Options Exercise	$0	-10.8K	-50%	$0.00	10.8K	09 Aug 2021	Common Stock	10.8K	$63.00	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 15, 2021.
F2	Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.