AmirAli Talasaz - 08 Dec 2025 Form 4 Insider Report for Guardant Health, Inc. (GH)

Role
Co-Chief Executive Officer, Director
Signature
/s/ John G. Saia, as attorney-in-fact for AmirAli Talasaz
Issuer symbol
GH
Transactions as of
08 Dec 2025
Net transactions value
-$10,505,474
Form type
4
Filing time
10 Dec 2025, 21:33:24 UTC
Previous filing
02 Oct 2025
Next filing
05 Jan 2026
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Talasaz AmirAli Co-Chief Executive Officer, Director 3100 HANOVER STREET, PALO ALTO /s/ John G. Saia, as attorney-in-fact for AmirAli Talasaz 10 Dec 2025 0001753159

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction GH Common Stock Other $0 -387,946 -82% $0.000000 82,854 08 Dec 2025 Shares held by Talasaz Investments, L.P. F1
transaction GH Common Stock Other $0 +193,973 +800% $0.000000 218,223 08 Dec 2025 Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018 F1
transaction GH Common Stock Other $0 +193,973 +800% $0.000000 218,223 08 Dec 2025 Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018
transaction GH Common Stock Sale $1,563,124 -15,000 -6.9% $104.21 203,223 08 Dec 2025 Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018 F2
transaction GH Common Stock Sale $3,240,172 -30,760 -15% $105.34 172,463 08 Dec 2025 Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018 F3
transaction GH Common Stock Sale $449,440 -4,240 -2.5% $106.00 168,223 08 Dec 2025 Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018
transaction GH Common Stock Sale $1,563,124 -15,000 -6.9% $104.21 203,223 08 Dec 2025 Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018 F2
transaction GH Common Stock Sale $3,240,172 -30,760 -15% $105.34 172,463 08 Dec 2025 Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018 F3
transaction GH Common Stock Sale $449,440 -4,240 -2.5% $106.00 168,223 08 Dec 2025 Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Reflects changes in form of ownership from Talasaz Investments LP due to the transfer of shares to The AmirAli Talasaz 2018 Children's Remainder Trust dated 9/25/2018, and Maryam Eskandari 2018 Children's Remainder Trust, dated 9/25/2018.
F2 Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $104.00 to $104.75. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.
F3 Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $105.00 to $105.81. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.