| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Sanders Corazon (Corsee) D. | Director | C/O BEONE MEDICINES I GMBH, AESCHENGRABEN 27, 21ST FLOOR, BASEL, SWITZERLAND | /s/ Qing Nian, as Attorney-in-Fact | 01 Dec 2025 | 0001796536 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ONC | American Depositary Shares | Options Exercise | $417,772 | +2,627 | $159.03 | 2,627 | 26 Nov 2025 | Direct | F1 | |
| transaction | ONC | American Depositary Shares | Sale | $620,185 | -1,823 | -69% | $340.20 | 804 | 26 Nov 2025 | Direct | F1, F2 |
| transaction | ONC | American Depositary Shares | Sale | $275,349 | -804 | -100% | $342.47 | 0 | 26 Nov 2025 | Direct | F1, F3 |
| holding | ONC | Ordinary Shares | 57,226 | 26 Nov 2025 | Direct |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ONC | Share Option (Right to Buy) | Options Exercise | $0 | -34,151 | -100% | $0.000000 | 0 | 26 Nov 2025 | Ordinary Shares | 34,151 | $12.23 | Direct | F4, F5 |
| Id | Content |
|---|---|
| F1 | Each American Depositary Share represents 13 Ordinary Shares. |
| F2 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $340.04 to $340.68, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F3 | The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $342.42 to $342.675, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. |
| F4 | The number of securities underlying each option and the exercise price therefore are represented in ordinary shares. |
| F5 | The option shall become exercisable in full upon the earlier to occur of the first anniversary of the grant date or the date of the next annual general meeting; provided, however, that all vesting shall cease if the Reporting Person resigns from the board of directors (the "Board") or otherwise ceases to serve as a director, unless the Board determines otherwise. Unvested securities are subject to accelerated vesting upon a change in control or certain termination events. The option was granted under the Company's Independent Director Compensation Policy, as amended. |