| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Van Hauwermeiren Timothy | Director | C/O DENALI THERAPEUTICS INC., 161 OYSTER POINT BLVD., SOUTH SAN FRANCISCO | /s/ Tyler Nielsen, by power of attorney | 2025-11-06 | 0001816206 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | DNLI | Common Stock | Award | $0 | +10.6K | $0.00 | 10.6K | Nov 4, 2025 | Direct | F1, F2 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | DNLI | Stock Option (right to buy) | Award | $0 | +31.9K | $0.00 | 31.9K | Nov 4, 2025 | Common Stock | 31.9K | $14.92 | Direct | F3 |
| Id | Content |
|---|---|
| F1 | Each share is represented by a Restricted Stock Unit ("RSU") and a contingent right to receive one share of common stock of the Issuer. The RSU award vests over a four-year period, with 1/4th of the shares vesting on each anniversary of the grant date (or, for the last tranche that otherwise would vest on the fourth anniversary of the grant date, on such anniversary or, if earlier, on the day prior to the Company's next annual meeting of stockholders occurring after the third anniversary of the grant date), provided that he remains a non-employee director through the applicable vesting date. |
| F2 | Includes 10,632 unvested RSUs. |
| F3 | 25% of the shares subject to the option shall vest on November 4, 2026, and an additional 1/48 of the shares subject to the option vest each month thereafter, subject to the Reporting Person remaining a non-employee director of the Issuer through each such date |