| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Accardi Mario Alberto | President, Orexin Program | C/O CENTESSA PHARMACEUTICALS PLC, 3RD FL., 1 ASHLEY RD, ALTRINCHAM, CHESHIRE, UNITED KINGDOM | /s/ Iqbal Hussain, attorney-in-fact | 2025-06-23 | 0002074392 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| holding | CNTA | Ordinary Shares | 216K | Jun 13, 2025 | Direct | F1, F2 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| holding | CNTA | Share Option (right to buy) | Jun 13, 2025 | Ordinary Shares | 11.3K | $9.53 | Direct | F1, F3 | ||||||
| holding | CNTA | Share Option (right to buy) | Jun 13, 2025 | Ordinary Shares | 16.9K | $9.53 | Direct | F1, F4 | ||||||
| holding | CNTA | Share Option (right to buy) | Jun 13, 2025 | Ordinary Shares | 30.3K | $3.85 | Direct | F1, F5 | ||||||
| holding | CNTA | Share Option (right to buy) | Jun 13, 2025 | Ordinary Shares | 40K | $8.01 | Direct | F1, F6 | ||||||
| holding | CNTA | Share Option (right to buy) | Jun 13, 2025 | Ordinary Shares | 225K | $16.90 | Direct | F1, F7 |
| Id | Content |
|---|---|
| F1 | The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share. |
| F2 | Includes 25,150 Restricted Share Units ("RSUs") issued under the Centessa Pharmaceuticals plc Amended and Restated 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one Ordinary Share of the Issuer. |
| F3 | 1/48th of the shares subject to such option shall vest and become exercisable in substantially equal monthly installments with the first installment vesting on March 1, 2022. |
| F4 | Represents the vested portion of such option granted on February 1, 2022 that vests upon the achievement of applicable performance goals. |
| F5 | 1/48th of the shares subject to such option shall vest and become exercisable in equal monthly installments with the first installment vesting on March 1, 2023. |
| F6 | 1/48th of the shares subject to such option shall vest and become exercisable in equal monthly installments with the first installment vesting on March 1, 2024. |
| F7 | 1/48th of the shares subject to such option shall vest and become exercisable in equal monthly installments with the first installment vesting on March 1, 2025. |
Exhibit 24 - Power of Attorney