Ramiro Sanchez - Aug 12, 2025 Form 4 Insider Report for Alto Neuroscience, Inc. (ANRO)

Role: Director
Signature: /s/ Erin R. McQuade, Attorney-in-Fact
Stock symbol: ANRO
Transactions as of: Aug 12, 2025
Transactions value $: $8,681
Form type: 4
Date filed: 8/14/2025, 05:22 PM
Previous filing: Jun 18, 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Sanchez Ramiro	Director	C/O ALTO NEUROSCIENCE, INC., 650 CASTRO STREET, SUITE 450, MOUNTAIN VIEW	/s/ Erin R. McQuade, Attorney-in-Fact	2025-08-14	0001830326

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ANRO	Stock Option (right to buy)	Award	$0	+30.6K		$0.00	30.6K	Aug 12, 2025	Common Stock	30.6K	$3.18	Direct	F1, F2
transaction	ANRO	Stock Option (right to buy)	Award	$8.68K	+3.93K		$2.21	3.93K	Aug 12, 2025	Common Stock	3.93K	$3.18	Direct	F3, F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The shares underlying the option shall vest in 36 equal monthly installments commencing on September 12, 2025, subject to the Reporting Person's continuous service through each vesting date.
F2	The derivative securities were granted to the Reporting Person pursuant to the Issuer's Non-Employee Director Compensation Policy, and were not sold to the reporting person. As such, the reporting person did not pay any consideration for the derivative securities.
F3	1,383 shares underlying the option shall vest on September 30, 2025, and 2,545 shares underlying the option shall vest on December 31, 2025, subject to the Reporting Person's continuous service through each such vesting date.
F4	This option was issued to the Reporting Person pursuant to the Issuer's Non-Employee Director Compensation Policy in lieu of retainer fees of $8,682.07.