| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| American Century Investment Management, Inc. | 5.9% | 3.61M | 3.48M | American Century Investment Management, Inc. | /s/ John Pak / Senior Vice President | ||
| American Century Companies, Inc. | 5.9% | 3.61M | 3.48M | American Century Companies, Inc. | /s/ John Pak / Senior Vice President | ||
| Stowers Institute for Medical Research | 5.9% | 3.61M | 3.48M | Stowers Institute for Medical Research | /s/ Richard W. Brown / Chairman |