RTW INVESTMENTS, LP - Dec 31, 2024 Form SCHEDULE 13G/A Schedule Report for Spyre Therapeutics, Inc. (SYRE)

Filing Manager: RTW INVESTMENTS, LP
Reporting Manager: RTW Investments, LP
Security: Spyre Therapeutics, Inc. Common Stock, par value $0.0001 per share
Symbol: SYRE
Shares outstanding: 58.4M shares
Disclosed Ownership: 3.62M shares
Ownership: 6.2%
Form type: SCHEDULE 13G/A
Date filed: 2/14/2025, 09:00 AM
Date of event: Dec 31, 2024
SEC: View on sec.gov

Reporting Managers (2)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
RTW Investments, LP	6.2%	3.62M	0	3.62M	/s/ Roderick Wong, M.D.	Roderick Wong, M.D., Managing Partner
Roderick Wong, M.D.	6.2%	3.62M	0	3.62M	/s/ Roderick Wong, M.D.	Roderick Wong, M.D.