| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| Redmile Group, LLC | 8.2% | 13.2M | 0 | 13.2M | /s/ Jeremy C. Green | Managing Member | |
| Jeremy C. Green | 8.2% | 13.2M | 0 | 13.2M | /s/ Jeremy C. Green | Jeremy C. Green | |
| RedCo II Master Fund, L.P. | 4.7% | 7.23M | 0 | 7.23M | /s/ Jeremy C. Green | Managing Member of RedCo II (GP), LLC, general partner of RedCo II Master Fund, L.P. |