| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| Paradigm BioCapital Advisors LP | 8.6% | 1.75M | 1.75M | 0 | /s/ David K. Kim | David K. Kim / Authorized Signatory | |
| Paradigm BioCapital Advisors GP LLC | 8.6% | 1.75M | 1.75M | 0 | /s/ David K. Kim | David K. Kim / Authorized Signatory | |
| Senai Asefaw, M.D. | 8.6% | 1.75M | 1.75M | 0 | /s/ Senai Asefaw, M.D. | Senai Asefaw, M.D. | |
| Paradigm BioCapital International Fund Ltd. | 7.6% | 1.55M | 1.55M | 0 | /s/ David K. Kim | David K. Kim / Authorized Signatory |